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Frequency and distribution of ABO and Rh Blood Group Antigens in Healthy Blood Donors at the Blood Bank of a Tertiary Care Hospital in Gandhinagar, Gujarat, India
- Author Details:
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Rupali Patil
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Vandana Patel
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Minesh B. Gandhi
Introduction: There are many blood group systems to classify red blood cells based on the presence of inherited antigens on their surface. Blood group antigens are inherited antigens and they already appear early in intrauterine life and remain constant through out life. Out of all antigens, two most important antigens are ABO and Rh antigens and they mostly found on RBCs surface and on platelets in blood. The human blood groups were first discovered by scientist Karl Landsteiner in 1901. ABO and RhD testing is the most frequently performed test in blood banking.
Aims and Objectives: To know the distribution frequency of other blood groups in healthy and adult blood donor, to compare this study data with other study data in other states of India and all over the world and to make documentation of a blood group data registry.
Materials and Method: Present study was conducted at Gujarat Medical Education and Research Society Medical College attached General Hospital, Gandhinagar, a tertiary care teaching Gujarat Government hospital. All blood donors were done counselling as per NACO guidelines and considered fit for blood donation were included in this study. Total 6853 blood donors were considered physically screened and declared fit and accepted for blood donation.
Results: Out of the total 6853 blood donors, 6508 (94.97%) were males and 345 (5.03%) were female and 6504 (94.9%) donors were of Rhesus ‘D’ positive and 349 (5.1%) were of Rhesus ‘D’ negative. In present study, blood group B was found to be the commonest blood group.
Conclusions: Female blood donors were very low because their haemoglobin level was below the required criteria and this needs to be increased by high quality of food and health status. The blood group of each and every person must be indicated on their driving licenses, aadhar card, PAN card and school/office identity cards. This study is most important for management of blood bank inventory and transfusion services to the needy patients.
Keywords: Blood group, Blood donors, Red blood cells, Replacement, Voluntary
References
- International Society of Blood Transfusion. Red celli mmunogenetics and blood group terminology. http:// www.isbtweb.org/ working-parties/ red-cell immunogenetics-and-blood-group-terminology. Accessed on 27 July 2016.
- Mathew E, Godwin N. Distribution of ABO and Rh-D blood groups in the Benin area of Niger-Delta: Implication for regional blood transfusion. Asian Journal of transfusion Science. 2008;2:1-3.
- Firkin F, Chesterman C, Penington D, Rush B. Blood groups; blood transfusion; acquired immune deficiency syndrome. In: de Gruchy’s clinical hematology in medical practice. 5thed, New Delhi, Oxford University Press; 1989. p. 475-96.
- "Table of blood group systems". International Society of Blood Transfusion (ISBT). Oct 2008, Available at: http://ibgrl.blood.co.uk/isbt.(Last accessed 28 Feb 2016).
- Daniels G, Castilho L, Flegel WA, Fletcher A, Garratty G, et al. (2009) International Society of Blood Transfusion Committee on terminology for red blood cell surface antigens: Macao report. Vox Sang 96:153-156.
- Harmening DM, Firestone D. The ABO blood group system. In: Harmening DM, editor Modern Blood Banking and Transfusion Practices.5th ed. Philadelphia, USA: FA Davis Company; 2005:108-32.
- Jaff MS. ABO and Rhesus blood group distribution in Kurds. J Blood Med 2010;1:143-6.
- Von decastella A, Sturli A. Ureber die isoag-glutinine in serumgesunder and Kranaker Men-schen. Mfiner Med WSchr. 1902;49:1090-5.
- Molison PL. Blood transfusion in clinical medicine. 6th ed. Oxford UK: Blackwell Scientific Publication; 1979.
- Roback JD, editor. Technical Manual.17th ed. USA: American Association of Blood Banks;2011.
- Harvey W (1928) Exercitatio Anatomica de Motu Cordis et Sanquinis in Animalibus. An Anatomical Exercise on the Motion of the Heart and Blood in Animals.
- Blundell J. Experiments on the Transfusion of Blood by the Syringe. Med Chir Trans. 1818;9:56-92.
- Sidhu S. Distribution of the ABO blood groups and Rh (D) factor among the scheduled caste population of Punjab group markers among the four scheduled caste. Anthropologist. 2003;5:203–4.
- Pramanik T, Pramanik S. Distribution of ABO and Rh blood groups in Nepalese medical students: a report. East Mediterr Health J. 2000;6:156–8.
- Dean L. The ABO blood group .In: Blood Groups and Red Cell Antigens. Bethesda (MD): National Center for Biotechnology Information (US);2005. Available from: http://www.ncbi.nlm.nih.gov/books/NBK2267/
- Garraty G, Dzik W, Issitt PD, Lubin DM, Reid ME, Zelinski T. Terminology for blood group antigens and genes-historical origins and guideline in the new millennium. Transfusion. 2000;40:477–89.
- Enosolease EM, Bazuaye GN. Distribution of ABO and Rh-D blood groups in the Benin area of Niger-Delta: Implication for regional blood transfusion. Asian J Transfus Sci. 2008;2:3-5.
- Voluntary Blood donation Programme. An operational Guideline. National AIDS Control Organisation .Ministry of Health and Family Welfare. Government of India. Available at http://naco.gov.in/upload/Policies%20&%20Guidelines/2 9,%20voluntary%20blood%20donation.pdf. (Last accessed on 28 Feb 2016).
- Lewis SM, Bain JB, Imelda B. Dacie and Lewis Practical Haematology. 9th ed. Livingstone: Churchill;2001. p.483-503.
- Patel PA, Patel SP, Shah JV, Oza HV. Frequency and distribution of blood groups in blood donors in western Ahmedabad – a hospital based study. National J. Med. Res.2012;2(2):207-210.
- Wadhwa MK, Patel SM, Kothari DC, Pandey M, Patel DD. Distribution of ABO and Rhesus-D groups in Gujarat, India: a hospital based study. Indan J Ped Oncol.1998; 19 (4):137–41.
- Parul G, Saloni U, Sanjay SC, Uman H, Ishwer T. Prevalence of ABO and Rhesus Blood Groups in blood donors: A study from a tirtiary care teaching hospital of Kumaon region of Uttarakhand. Journal of clinical and diagnostic research.2014;8(12):16-19.
- Chandra T, Gupta A. Frequency of ABO and rhesus blood groups in blood donors. Asian J Transfus Sci. 2012;6:52-53.
- Kaur H, Khanna A, Manjari M, Khanna M. Prevalence of ABO blood groups and rhesus (Rh) factor in the population residing in and around Amritsar, Punjab (a 4- year study from June 2007 to June 2011). Asian J Transfus Sci. 2013;7(2):159.
- Giri PA, Yadav S, Parhar GS, Phalke DB. Frequency of ABO and Rhesus Blood Groups: A study from a rural tertiary care teaching hospital in India. Int J Biol Med Res.2011;2(4):988–90.
- Nag I, Das SS. ABO and Rhesus blood groups in potential blood donors at Durgapur Steel city of the district of Burdwan, West Bengal. Asian J. Transfus Sci. 2012;6(1): 54-55.
- Girish CJ, Chandrashekhar TN, Ramesh Babu K, Kantikar SM. ABO and Rhesus blood group distribution among Malnad region blood donors. Research and Reviews in Biomedicine and Biotechnology (RRBB).2011;2(3):25-30.
- Periyavan A, Sangeetha S K, Marimuthu P, Manjunath BK, Seema DM. Distribution of ABO and Rhesus-D, groups in and around Bangalore. Asian J Transfus Sci. 2010;4 (1):41.
- Khattak ID, Khan TM, Khan P Shah SM, Khattak ST, Ali A. Frequency of ABO and Rhesus blood group in district Swat, Pakistan. J Ayub Med Coll. 2008; 20(4):127-29.
- Mollison PL, Engelfriet CP, Conteras M. The Rh blood Group system. In Blood Transfusion in Clinical Medicine, 9th Edition. Oxford: Black well Scientific Publication.1993;2008–09.
- Australian Red Cross Society. All about blood. URL; www. donateblood.com.au/all-aboutblood/blood-types.
- Bashwari LA, Al Mulhim AA, Ahmad MS, Ahmed MA: Frequency of ABO blood groups in Eastern region of Saudi Arabia. Saudi Med J. 2001;22:1008–12.
- Pramanik T, Pramanik S, Distribution of ABO and Rh blood groups in Nepalese medical students: a report. East Mediterr Health J. 2000;6(1):156-58.
- Kaur H, Mannan R, Manjari M, Sharma S, Garg T, Bhasin TS. Blood donor deferral analysis: A tertiary care centre experience. Accepted in APALM. Vol 3. Issue 4. (02 August 2016)
- Kasraian L, Negarestani N. Rates and reasons for blood donor deferral, Shiraz, Iran. A retrospective study. Sao Paulo Med J 2015;133(1):36-42.
How to Cite This Article
Vancouver
Patil R, Patel V, Gandhi MB. Frequency and distribution of ABO and Rh Blood Group Antigens in Healthy Blood Donors at the Blood Bank of a Tertiary Care Hospital in Gandhinagar, Gujarat, India [Internet]. Indian J Pathol Oncol. 2017 [cited 2025 Oct 19];4(4):586-590. Available from: https://doi.org/
APA
Patil, R., Patel, V., Gandhi, M. B. (2017). Frequency and distribution of ABO and Rh Blood Group Antigens in Healthy Blood Donors at the Blood Bank of a Tertiary Care Hospital in Gandhinagar, Gujarat, India. Indian J Pathol Oncol, 4(4), 586-590. https://doi.org/
MLA
Patil, Rupali, Patel, Vandana, Gandhi, Minesh B.. "Frequency and distribution of ABO and Rh Blood Group Antigens in Healthy Blood Donors at the Blood Bank of a Tertiary Care Hospital in Gandhinagar, Gujarat, India." Indian J Pathol Oncol, vol. 4, no. 4, 2017, pp. 586-590. https://doi.org/
Chicago
Patil, R., Patel, V., Gandhi, M. B.. "Frequency and distribution of ABO and Rh Blood Group Antigens in Healthy Blood Donors at the Blood Bank of a Tertiary Care Hospital in Gandhinagar, Gujarat, India." Indian J Pathol Oncol 4, no. 4 (2017): 586-590. https://doi.org/