A prospective study and correlation of cytological, cell-block and histopathological diagnosis of breast lesions

Original Article

Author Details : Sowmya S Manjunath, Ankita Paul*

Volume : 8, Issue : 3, Year : 2021

Article Page : 352-358


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Introduction: Breast carcinoma is the second most common cancer in the world and establishing an early diagnosis is clinically very important. Fine needle aspiration cytology (FNAC) is the fast, reliable and ideal initial diagnostic modality for the diagnosis of these lesions.
Materials and Methods: This is a cross-sectional prospective study of 12 months duration. A total of 160 patients underwent FNAC of palpable breast lump/lumps. A cell-block preparation was done for 80 cases and the histopathological examination has been performed on all the 160 cases.
Materials and Methods: The cytomorphological diagnosis, cell-block diagnosis and histopathological diagnosis were correlated using suitable statistical methods.
Results: Out of 160 patients, on cytological examination, 107 cases (67%) were benign and 53cases (33%) were malignant. On histopathological examination, 104 cases (65%) were benign and 56 cases (35%) were malignant. On examination of cell block, two cases which were indeterminate in FNAC turned out to be malignant.
Conclusion: FNAC plays a main diagnostic role as an out-patient procedure which gives rapid diagnosis. FNAC when combined with cell-block can give more accurate diagnosis.

Keywords: FNAC, Breast disease, Cytology, Cell block.

How to cite : Manjunath S S, Paul A, A prospective study and correlation of cytological, cell-block and histopathological diagnosis of breast lesions. Indian J Pathol Oncol 2021;8(3):352-358

Copyright © 2021 by author(s) and Indian J Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (creativecommons.org)

Article History

Received : 13-06-2021

Accepted : 23-06-2021

Available online : 12-08-2021

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