Malignant brenner tumor –A rare case report with immunohistochemical study

Case Report

Author Details : Kalaivani Selvam, Banushree Chandrasekhar Srinivasamurthy*, Sabita Pulavarthi, Ramchandra V Bhat

Volume : 8, Issue : 2, Year : 2021

Article Page : 312-315

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Background: Malignant Brenner tumor (MBT) is a rare epithelial ovarian tumor that has been not well documented in the literature. Clinical features, serum markers, and imaging studies are non-specific for the diagnosis.
Case Report: We report a case of a 76year old female who presented with complaints of bleeding per vaginum and underwent laparotomy. After an extensive sampling of the specimen, histopathological examination revealed features of malignant Brenner tumor. To support the histological diagnosis
immunohistochemical markers were done.
Result: The non-specific findings on ultrasonography were resolved with histopathological and immunohistochemical markers.
Conclusion: MBT is a rare tumor with no specific clinical or imaging findings. The application of histopathological criteria and immunohistochemistry aids in definitive diagnosis.

Keywords: Malignant brenner, Transitional epithelium, p63.

How to cite : Selvam K , Srinivasamurthy B C, Pulavarthi S , Bhat R V, Malignant brenner tumor –A rare case report with immunohistochemical study. Indian J Pathol Oncol 2021;8(2):312-315

Copyright © 2021 by author(s) and Indian J Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (

Article History

Received : 25-01-2021

Accepted : 13-02-2021

Available online : 19-05-2021

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