Correlation of various histopathological lesions of prostate with serum prostate specific antigen and gleason grading


Original Article

Author Details : Dharamveer Sihag*, Preeti Laddha

Volume : 8, Issue : 2, Year : 2021

Article Page : 213-217

https://doi.org/10.18231/j.ijpo.2021.042



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Abstract

Introduction: Present study was conducted to determine the age distribution of patients with prostatic lesions, prevalence of distribution of various prostatic lesions and to study correlation of histopathological types of prostatic lesions with prostate specific antigen (PSA).
Materials and Methods: A total 246 prostatic needle biopsies from patients of all age groups were included in the study. After studying the histopathological features, the diagnosis of various types of prostatic lesions was made and Gleason’s scoring was done in cases of prostatic carcinoma. Subsequently, a correlation was made between the histopathological diagnosis and serum PSA level.
Results: The Mean±Sd of age is 69.7±9.9 years. In pure inflammatory lesions, LGPIN, HGPIN, BPH, and BPH with prostatitis majority had PSA level <4ng> Conclusion: Histopathological diagnosis and grading plays an important role in the management of prostatic cancer. For satisfactory management of patient, a high degree of the awareness of the advances along with team approach has become imperative.

Keywords: BPH, LGPIN, HGPIN, PSA, Pure inflammatory lesions.


How to cite : Sihag D , Laddha P , Correlation of various histopathological lesions of prostate with serum prostate specific antigen and gleason grading. Indian J Pathol Oncol 2021;8(2):213-217


Copyright © 2021 by author(s) and Indian J Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)



Article History

Received : 03-01-2021

Accepted : 06-01-2021

Available online : 19-05-2021


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https://doi.org/10.18231/j.ijpo.2021.042


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