A clinicopathological analysis of non-infectious granulomatous dermatoses

Original Article

Author Details : Seema Bijjaragi, Aarthy C N*, Gautam Balaram, Melanie Pinto

Volume : 8, Issue : 1, Year : 2021

Article Page : 128-132


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Background: Non-infectious granulomatous dermatoses involves a broad group of distinct reactive inflammatory conditions. They have overlapping morphological and clinical features and hence pose a diagnostic challenge to differentiate from other granulomatous dermatoses and affect the management of the patient.
Aims and Objectives: To study the histopathological patterns of non-infectious granulomatous dermatoses and to correlate with clinical features.
Materials and Methods: It is a retrospective study for a period of 5 years at a tertiary care centre in central Karnataka.
Results: In the present study, out of 7273 skin biopsies there were 34 cases of non-infectious granulomatous dermatoses. Out of these 34 cases, granuloma annulare (50%) was the most common non-infectious granulomatous lesion followed by annular elastolytic giant cell granuloma (14%), foreign body granuloma (9%), tattoo granuloma (9%) perforating folliculitis (9%), xanthoma(6%) and xanthelasma (3%).
Conclusion: Non-infectious granulomatous disorders of skin encompass a large group of disorders with overlapping features. Thus adequate clinical data and subtle histological findings are important for specific diagnosis which provides better patient management.

Keywords: Granulomatous dermatoses, Granuloma annulare, Annular elastolytic giant cell granuloma, Xanthogranuloma.

How to cite : Bijjaragi S , Aarthy C N, Balaram G , Pinto M , A clinicopathological analysis of non-infectious granulomatous dermatoses. Indian J Pathol Oncol 2021;8(1):128-132

Copyright © 2021 by author(s) and Indian J Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)

Article History

Received : 24-08-2020

Accepted : 21-09-2020

Available online : 20-02-2021

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