Author Details :
Volume : 7, Issue : 1, Year : 2020
Article Page : 104-108
Introduction: The nasal cavity, paranasal sinuses and nasopharynx form a functional unit of the nose
and its anatomical location makes it the fertile land for exposure to several pathogenic factors Nasal
symptoms are one of the commonest reasons for which patient seeks medical advice and as the nose
occupies prominent anatomical position on the face, early diagnosis and treatment of any scarring or
ulcerative lesion is imperative. Clinically and radiologically benign and malignant lesions are difficult
to differentiate. So, histopathology remains main diagnostic approach for the lesions of sino-nasal tract. In
present study attempt is made to study histopathological spectrum of sino-nasal lesions with regard to age
and sex distribution.
Materials and Methods: All indoor and outdoor patients attending ENT department with complains of
nasal mass, obstruction, discharge, bleeding and others were selected for this study during tenure of 2014-
2018. All the tissues were fixed in 10% formalin, processed, stained with H and E and studied for various
Results: In present study, out of total sinonasal lesions, non-neoplastic lesions were highest(60%) followed
by benign (24.62%) and malignant lesions (15.38%) respectively. Malignant lesions were found in fifth,
sixth and seventh decade mainly. All sino-nasal lesions presented with common symptom of nasal
obstruction without discrimination of non-neoplastic and neoplastic lesions. Males showed maximum
(70.76%) lesions of all categories.
Conclusion: Majority of sinonasal lesions present with complain of obstruction, out of which majority
were non-neoplastic lesions, hence histopathological examination remains main stay to differentiate nonneoplastic,
benign and malignant lesions to avoid un-necessary surgery.
Keywords: Histopathological study, Sino-nasal lesions, Nasopharyngeal lesions.
How to cite : Neb V, Bhagat V, Patel P R, Rupareliya N , Gandhi N, Spectrum of neoplastic sino-nasal lesions at tertiary care centre. Indian J Pathol Oncol 2020;7(1):104-108
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